Compartmentalize the system to have "safe" areas where trust boundaries can be unambiguously drawn. Do not allow sensitive data to go outside of the trust boundary and always be careful when interfacing with a compartment outside of the safe area.
Ensure that appropriate compartmentalization is built into the system design, and the compartmentalization allows for and reinforces privilege separation functionality. Architects and designers should rely on the principle of least privilege to decide the appropriate time to use privileges and the time to drop privileges.
Check the results of all functions that return a value and verify that the value is expected.
In Windows, make sure that the process token has the SeImpersonatePrivilege(Microsoft Server 2003). Code that relies on impersonation for security must ensure that the impersonation succeeded, i.e., that a proper privilege demotion happened.